Diabetes means your blood glucose, or blood sugar , levels are too high. With type 2 diabetes, the more common type, your body does not make or use insulin well. Insulin is a hormone that helps glucose get into your cells to give them energy. Without insulin, too much glucose stays in your blood.
Type 2 Diabetes in Adults: New Diagnosis - What You Need to Know
Related to adult-onset diabetes: diabetes mellitus , type 2 diabetes. Type 2 diabetes. All rights reserved. Copyright , , by Random House, Inc.
Adult-onset autoimmune diabetes: comparative analysis of classical and latent presentation
A new treatment for adult-onset diabetes and obesity developed by researchers at Indiana University and the German Research Center for Environmental Health has essentially cured lab animals of obesity, diabetes and associated lipid abnormalities through improved glucose sensitivity, reduced appetite and enhanced calorie burning. The new findings were published today in Nature Medicine. These preclinical results advance the clinical work the team announced last year that a peptide combining the properties of two endocrine hormones, GLP-1 and GIP, was an effective treatment for adult-onset diabetes. This new molecule includes a third hormone activity, glucagon. The molecules are called triple agonists -- three hormones combined molecularly that can bind to and activate receptors to produce certain biological responses.
Adult-onset autoimmune diabetes is a heterogeneous disease that is characterized by a reduced genetic load, a less intensive autoimmune process and a mild metabolic decompensation at onset compared with young-onset type 1 diabetes mellitus T1DM. The majority of patients with adult-onset autoimmune diabetes do not require insulin treatment for at least 6 months after diagnosis. The extensive heterogeneity of adult-onset autoimmune diabetes is apparent beyond the distinction between classic adult-onset T1DM and LADA. LADA is characterized by genetic, phenotypic and humoral heterogeneity, encompassing different degrees of insulin resistance and autoimmunity; this heterogeneity is probably a result of different pathological mechanisms, which have implications for treatment.